Compact CRISPR alternative uses bacterial proteins to insert large DNA segments for human gene therapy and cellular engineering
https://phys.org/news/2026-10-compact-crispr-alternative-bacterial-proteins.html "gene-editing payload constraints require bulky delivery vectors limiting therapeutic scope complex genetic sequence insertion... overcome leveraging naturally occurring, smaller bacterial enzymatic complexes targeting specific genomic sites, precisely/ seamlessly integrating multi-kilobase DNA fragments... reduced molecular size allows these protein complexes to be packaged far more efficiently into standard clinical delivery vehicles... entire gene replacements in addition to minor edits"