Molecular editing enables precise atom insertion/ removal within established core skeleton without synthesizing compound from scratch
https://www.eurekalert.org/news-releases/1132073
"compresses timeline for late-stage functionalization in medicinal chemistry, optimizing drug discovery/ molecular design pipelines... Alkyl Swap replaces methyl group of N-methylamines (molecular class found in countless proteins, neurotransmitters, pharmaceuticals) with more intricate molecular fragments... no complex multi-step processes, sensitive metal catalysts, strictly air-free and water-free environments... demonstrated on fluoxetine, duloxetine, sertraline derivatives... creation of diverse molecular libraries"
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