Microscopy rapidly captures high-resolution thick biological tissue images without specialized hardware/ destructive chemical sectioning

https://www.eurekalert.org/news-releases/1131100

"trade-off between ultra-sharp. expensive oil-immersion lenses seeing few mm deep/ cheap air lenses blurring when viewing chemically cleared transparent tissues... overcome using Hybrid Solid–Liquid Optics: highly scalable pairing simple curved solid lens/ matched immersion liquid allows inexpensive air lenses to capture sharp, blur-free images several cm deep... integrated into compact, projector-based light-sheet microscope... training AI diagnostic models: 3D mapping of neural circuits/ cancer biopsies"