cancer 2026

Combination treatment benefits patients with advanced breast cancer that has spread to the brain

Scientists create cancer-fighting immune cells right in the body

AI-designed photosensitizer achieves record performance for cancer photodynamic therapy

Researchers make breakthrough in biomedical imaging and cancer treatment

Blocking a single protein could make HPV-positive tumors treatable

Tiny tools, sharp aim: Nanobodies target tumors with precision
https://phys.org/news/2026-03-tiny-tools-sharp-aim-nanobodies.html

Prodrug lipid nanoparticle could unlock universal immunotherapy for solid cancers

Advance could lead to safer, more effective T cell therapies for prostate cancer and other solid tumors

New fishhook bonds help T cells stick longer to prostate cancer cells

Scientists turn probiotic bacteria into tumor-hunting cancer killers

Sono-tribocatalytic therapy provokes PANoptosis in cancer cells

Immune cell ‘bloodhounds’ track cancer cells’ unique metabolic signatures, eliminate tumors in mice

A new glioblastoma target: Blocking CD47 protein's tumor-driving role may slow growth

Genetic weakness may help target deadly small cell neuroendocrine cancers

A protein may help revive exhausted T cells in cancer immunotherapy

Protein modification discovery opens cancer therapy possibilities

Scientists engineer a Trojan Horse to conquer aggressive brain cancer

A new immunotherapy target? How SRC-3 in Tregs may reshape solid-tumor treatment

Light-activated nanoparticles trigger copper overload to kill cancer cells

Experimental cancer drug tricks immune system into attacking tumors like a virus

Boron neutron capture therapy may extend survival in patients with malignant tumors
https://www.eurekalert.org/news-releases/1121666

Emerging light-powered cancer treatment gets a nanotech upgrade

Snail inspired soft robots to transform precision drug delivery in bowel cancer

New genetic ‘roadmap’ advances precision therapy for intrahepatic cholangiocarcinoma

SCD1 inhibitor aramchol, regorafenib, and metformin combine to kill uveal melanoma cells

Targeting tumor supporting cells: Advancing CAR T success in pancreatic cancer

Heat-activated skin patch can kill melanoma cells without surgery

Molecular system can distinguish and neutralize cancer cells, paving the way for 'smart' drugs

Restoring mitochondrial function in dendritic cells improves antitumor immune responses and enhances immunotherapeutic efficacy

Cancer immunotherapy that turns tumors into their own vaccines
https://www.eurekalert.org/news-releases/1122223

How pancreatic tumors thwart an iron-driven demise

Lentinus edodes-derived β-glucan inhibits human cervical cancer progression through DMBT1

First-in-class dual HIF inhibitors eliminate breast, colorectal, melanoma, and prostate tumors in mice when combined with immunotherapy

Mechanisms behind tumor suppressor BAP1 highlight new treatment strategies for aggressive cancers

Innovative targeted therapy halts prostate cancer spread to the bone

Dual-drug nanotherapy crosses blood–brain barriers improved survival in preclinical glioblastoma models
https://www.eurekalert.org/news-releases/1122882

Natural alkaloid gramine suppresses triple-negative breast cancer by inducing ferroptosis via the CUL3–MTDH axis

Treating tumors independently of oxygen

A single enzyme keeps neuroblastoma alive. Researchers just learned how to shut it off

Previously unknown chromatin regulation mechanism with therapeutic potential for pediatric cancer
https://medicalxpress.com/news/2026-04-scientists-uncover-previously-unknown-chromatin.html

New method makes cancer cells more visible to immune system

Study identifies strategy to overcome radiation therapy resistance in lung cancer

Researchers find new target to sensitize pancreatic tumors to immunotherapy

Insilico’s new cancer therapy: Discovering selective PKMYT1 inhibitors via sulfur-lone pair interactions
https://www.eurekalert.org/news-releases/1123412

Researchers map prostate immune niches, showing T cells persist months in mice

A counterintuitive molecular behavior opens new possibilities for cancer radiotherapy

Drugs at the right place, at the right time

Targeting senescent ADSCs in adipose tissue: Tongji University paves way for ovarian cancer therapy
https://www.eurekalert.org/news-releases/1123730

Targeting stem-like cells in colorectal cancer
https://www.eurekalert.org/news-releases/1124139

New drug doubles 1-year survival in pancreatic cancer trial

CRISPR variant selectively targets tumor DNA

LINC00862–RBM47 positive feedback loop suppresses hepatocellular carcinoma progression

Aggregation‑induced‑emission luminogens functionalized MXene nanosheets for stimuli‑responsive hydrogel in pyroptosis‑mediated choroidal melanoma therapy

Biological shield can prevent skin cancer cells from transforming into aggressive metastatic forms

Global trial shows novel treatment for triple-negative breast cancer nearly doubles survival

mRNA vaccines follow unconventional immune path to destroy tumors

How mRNA cancer vaccines still destroy tumors when a key immune cell is missing

Scientists crack an 'undruggable' childhood cancer protein, opening a path to treatments for neuroblastoma

AACR: Zedoresertib and lunresertib combination shows promising antitumor activity

Investigational KRAS(ON) inhibitor zoldonrasib showed effective and durable responses in patients with advanced G12D-mutated lung cancer

New antibody-drug conjugate shows clinical benefit for advanced platinum-resistant ovarian cancer

Next-generation KRAS G12C inhibitor elisrasib elicited promising response rates in patients with advanced lung cancer https://www.eurekalert.org/news-releases/1124799 see also: Experimental KRAS G12D drug slows cancer growth, shrinks tumors in early test https://medicalxpress.com/news/2026-04-experimental-kras-g12d-drug-cancer.html

Groundbreaking bowel cancer trial follow-up shows zero relapses

New KIR-CAR T cell therapy shows promise in multiple solid cancers

Dana-Farber phase 2 trial shows deep and lasting responses to car t-cell therapy for high-risk smoldering multiple myeloma

Preventing cancer progression/ surgery for majority of patients with precancerous oral lesions
https://www.eurekalert.org/news-releases/1125002

New drugs raise hopes of pancreatic cancer breakthrough

Candidate breast cancer drug overloads tumors with surge of toxic lipids

New targeted therapy shows promise against aggressive childhood and adult cancers

Dual-pathway blockade therapy offers hope for rare, hard-to-treat gynecological clear cell cancers

Unleashing natural killer cells against cancer

Discovery of a novel vulnerability in aggressive lymphoma could change future therapy

Exploiting a new vulnerability that targets zombie cells as an anticancer therapy

SKKU photoactivatable oligoelectrolytes engendering pyroptotic vesicles
https://www.eurekalert.org/news-releases/1125663

RagC senses β-hydroxybutyrate abundancy to suppress mTORC1 and tumor growth

Glycocalyx engineering advances adoptive cell therapies for B lymphoma

Damaged mitochondria leak double-stranded RNA within pancreatic cancer cells causing inflammation that fuels cancer growth; inhibiting this process kills cancer cells in mice
https://www.eurekalert.org/news-releases/1125898

Umbilical cord blood transplant with pooled stem cell product shows 96% survival and no GVHD in leukemia patients

Drugging the undruggable: Scientists achieve million-fold leap in targeting elusive cancer proteins

CDI scientists identify key dynamic to boost cancer treatments while limiting stem cell transplant rejection

UIC scientists source anti-cancer treatment in bacteria

New dual-target drug may help overcome immunotherapy resistance in pancreatic cancer

Scientists recruit red blood cells to deliver genetic cargo with instructions to kill cancer

Cancer cells can rewrite RNA messages, creating new drug targets in aggressive tumors

Preclinical efficacy of experimental peptide therapy suggests a new target for metastatic breast cancer treatments, UTHealth Houston researchers find

New copper nanozyme shows powerful tumor suppression with high precision

New natural molecule boosts CAR-T therapy and turns cold tumors hot
Theranostic approach for radioimmunotherapy achieves curative responses in colorectal cancer tumors
https://www.eurekalert.org/news-releases/1126582

Proper protein recycling can help burned out T cells regain their fighting capabilities to help clear tumors
https://www.eurekalert.org/news-releases/1126578

AI-assisted approach identifies IRS4 as a promising drug target in multiple solid tumors

Blocking energy metabolism may help treat aggressive pediatric brain tumor

Stem cell memory CAR T cells achieve complete remissions at low doses without chemotherapy preconditioning

Destabilizing DNA repair proteins restores tumor sensitivity to PARP inhibitor therapy

T cells secrete DNA to boost the immune system's cancer-fighting ability

New copper nanozyme shows powerful tumor suppression with high precision

Blocking a cellular inflammation process could result in effective therapy for pancreatic cancer

Researchers find potential one-two punch against triple-negative breast cancer

Complete remission of aggressive pituitary tumor achieved through immunotherapy

One missing metabolic step can turn cancer's DNA-copying machinery into a lethal weakness

Yanghe Decoction inhibits osteosarcoma progression

lncRNA ROLLCSC: A prognostic marker and therapeutic target for lung adenocarcinoma

RAS inhibitor daraxonrasib demonstrates initial anti-tumor activity in pancreatic cancer
https://www.eurekalert.org/news-releases/1127182 see also: RAS(ON) inhibitor daraxonrasib shows promising results in advanced pancreatic cancer phase 1/2 study
https://www.eurekalert.org/news-releases/1127144 RAS(ON) inhibitor doubles median overall survival in results of phase 3 trial for patients with metastatic pancreatic cancer https://www.eurekalert.org/news-releases/1130044  (note: these are #1, especially combined with IBRX) see also Vega startup A targeted combination therapy achieves effective pancreatic cancer regression and prevents tumor resistance https://www.pnas.org/doi/10.1073/pnas.2523039122

Mount Sinai study identifies new strategy to overcome immunotherapy resistance in colorectal cancer

IL-10 gene therapy boosts immune attack against liver cancer in mice

Technology receives FDA approval for breast cancer treatment

Leukemia stem cells cause treatments to fail, but findings open new avenues to overcome resistance
https://medicalxpress.com/news/2026-05-leukemia-stem-cells-treatments-avenues.html

Novel nanoparticle therapy using manganese could improve cancer treatment

Nanoparticles overcome drug-resistant cancer via sequential drug release and photothermal therapy

China Innovative Drug NHWD-870 Receives Breakthrough Therapy Designation, Bringing New Hope of Survival to NUT Carcinoma Patients
https://www.prnewswire.com/news-releases/china-innovative-drug-nhwd-870-receives-breakthrough-therapy-designation-bringing-new-hope-of-survival-to-nut-carcinoma-patients-302766935.html

DNA ‘barcodes’ help researchers pinpoint gold nanoparticles that can strike cancer at its power source
https://www.eurekalert.org/news-releases/1127877

First-in-human trial demonstrates promise of implantable cytokine factories for ovarian cancer

Gene-edited stem cell transplant shows promise for aggressive blood cancers

Personalized vaccine shows promise against aggressive brain cancer

Novel molecular marker may improve prostate cancer treatment

New drugs could wipe out the “zombie cells” linked to cancer and aging

New McMaster-made drug candidate shows promise as a brain cancer treatment

MIT-MGH team finds a new approach to cancer vaccination that yields more powerful T cells

New drug candidate that reprograms the immune system shows promise as a brain cancer treatment

Experimental drug shrinks advanced kidney tumors, clears cancer in one patient

Experimental drug shows promise for some patients with advanced prostate cancer

New targeted radiopharmaceutical therapy induces remission in pancreatic cancer model

Study reveals promising new therapy for non-Hodgkin lymphoma

Novel CAR T cell therapy moves into clinical studies

Reversing T cell exhaustion improves effectiveness of myeloma immunotherapies

Novel molecular marker may improve prostate cancer treatment

A new approach to cancer vaccination yields more powerful t cells

Common asthma drug shows promise against aggressive cancers

Cytokine-armored CAR-T cell therapy helps eliminate aggressive brain tumors in preclinical study

Boosting anti‑tumor immunity by expanding immune cell pool recognizing cancer cells/ cancer antigens
https://www.eurekalert.org/news-releases/1128778

Researchers identify new drug targets for hard-to-treat cancers

Targeting inflammation may help overcome drug resistance in colon cancer

Breast cancer drug is effective for treatment-resistant uterine cancer

Garvan scientists capture ‘housekeeping’ immune cells attacking live melanoma

FDA approves Inqovi for acute myeloid leukemia

On-chip targeted cell killing via unprecedented high-efficiency singlet oxygen generation
https://www.eurekalert.org/news-releases/1129503

Researchers puts cancer under pressure to slow tumor growth

Transfer learning-assisted discovery of novel gp130 inhibitors for colorectal cancer therapy

Sanguinarine: The “switch” that turns BiP against lung cancer

Targeted platinum-antibody conjugates boost tumor visibility to the immune system

KRAS degradation induces rapid lung cancer regression in preclinical mouse models

Naturally occurring molecule slows melanoma growth and reverses drug resistance
https://www.eurekalert.org/news-releases/1129708

Potential to significantly influence the course of leukemia
https://www.eurekalert.org/news-releases/1129736

Androgen receptor (AR) represses LRH-1 in prostate cancer

Targeting UCP2 rewires metabolism to suppress leukemia progression

Researchers identify new target to prevent aggressive form of prostate cancer

Multidrug treatment using nanofibers shows promise for glioblastoma

Immune memory cells capable of producing antibodies against cancer
https://www.eurekalert.org/news-releases/1130033

Common anemia medication shows unexpected potential in cancer treatment

Targeted drug outperforms chemotherapy for patients with hard-to-treat lung cancer

New T-cell engager shows promise for advanced solid tumors

A peptide-targeted, hypoxia-responsive adeno-associated virus platform for tumor-selective delivery of chemokines and PNAi in non-small cell lung cancer

Long-term leukemia trial reveals MRD-triggered treatment may slow or prevent relapse

Nanofiber implant delivers three drugs, doubles survival in glioblastoma mice

Novel radiopharmaceutical therapy offers powerful treatment option for aggressive neuroendocrine tumors
https://www.eurekalert.org/news-releases/1129742 see also: New theranostic approach effectively detects and treats neuroendocrine prostate cancer https://www.eurekalert.org/news-releases/1129741

Targeted therapy reduces risk of lung cancer recurrence by 83% in rare genetic subtype

ASCO: Targeted therapy combo nearly doubles time without disease progression for patients with advanced colorectal cancer

Perioperative apalutamide in high-risk localized or locally advanced prostate cancer reduces risk of metastasis and death

Fovinaciclib for first-line therapy of advanced breast cancer

Cancer vaccine sustains 49 percent melanoma reduction after 5 years

Why some tumors resist immunotherapy: Blocking miR-25 may help turn 'cold' cancers 'hot'

First‑in‑human study tests gamitrinib designed to disrupt cancer cells’ energy systems

Novel prostate cancer treatment can reduce risk of disease progression by half, clinical trial shows

Nanoparticles boost delivery of lung cancer drugs 30-fold

Irradiation may help CAR-T cell therapy work better against solid tumors

New breakthrough in developing more personalized treatments for lung cancer

Engineered Salmonella deliver cancer-killing viruses, shrinking liver and pancreatic tumors in mice

UMass Amherst researchers combine bacteria and viruses to demonstrate a new way to fight cancer

Previously unrecognized immune response could enhance defense against cancer

A dual metabolic strike: Copper-based nano-PROTACs strengthen cuproptosis cancer therapy

UM Greenebaum Comprehensive Cancer Center offers innovative cell therapy for synovial sarcoma

Experimental drug combination shows early effectiveness in advanced kidney cancer

Worm tablet could be repurposed as brain cancer treatment

Researchers discover way to inhibit brain cancer's infiltration mechanism in glioblastoma

Experimental compounds trigger cancer cell death in KRAS-driven pancreatic cancer

A new route to kill resistant bladder cancer cells

Nanjing University: novel targeted therapy for EGFR-driven tumors using IVSA technology

Cancer cells' hunger may reveal new ways to track and slow tumors

Expedition to Antarctica advances research on potential melanoma treatment

Stopping cancer proteins before they even form?

Vitamin E-derived molecule enhances DNA-based nanostructures for drug delivery, imaging, therapeutics
https://www.eurekalert.org/news-releases/1131572

Scientists develop nanoparticle delivery system to target blood cancer cells

CRISPR enzyme precisely detects and shreds DNA in cancer mutations once considered undruggable

Oral therapy enables at-home treatment for acute myeloid leukemia

New antibody may boost KRAS-targeted lung cancer treatment after resistance emerges

Supercharged natural killer cells suppress solid tumors in mice

Cancer drug combo activates inflammatory signal that could boost immune response

Metal-free carbon monoxide prodrugs may help prevent cancer's deadly spread

This is how to beat the tumor cells that survive cancer therapy

Sugar-coated CAR-T cells survive longer and shrink lymphoma tumors in mice

Why the two main types of lung cancer respond differently to drugs that target blood vessels, a finding that opens the door to more effective therapies
https://www.eurekalert.org/news-releases/1132149

Researchers identify target with potential to improve CAR T-cell therapy response in patients with blood cancers

Experimental treatment directly kills prostate tumor cells while reawakening antitumor immunity

Light switch makes cancer vulnerable to attack

Why some cancers return: Robotic mini tumor tests point to new ways to target persister cells

Inducing cell death in pancreatic cancer cells

Hidden PIM1 pathway helps prostate cancer survive treatment, pointing to new drug strategy
https://medicalxpress.com/news/2026-06-hidden-pim1-pathway-prostate-cancer.html

New pancreatic cancer strategy kills KRAS-mutant tumor cells and extends survival in mice

U of Guelph prof discovers plant-based solution to target leukemia weakness

FAP-targeted radiopharmaceutical therapy shows broad effectiveness across multiple cancers

Personalizing treatment for an aggressive asbestos-linked cancer
https://www.eurekalert.org/news-releases/1132564

Colorectal tumors use mitochondrial complex II to stockpile iron, but eliminating it causes cell death

Rewired metabolism helps revive exhausted immune cells and boost cancer immunity

Inhibiting high levels of leukemia ABCD1 protein with jojoba could lead to new treatment option

Drug-free nanoparticles stop tumor growth by transmitting biological messages to immune cells

Removing a single gene makes colon cancer cells a target for immunotherapy
https://www.eurekalert.org/news-releases/1132817

Molecule found on cell surfaces may pave the way for new therapies against tumor progression

A new approach in anticancer vaccine development shows early success in targeting neuroblastoma

A renewable cell source for cancer immunotherapy could make off-the-shelf treatments possible

Algae microbots take aim at bladder cancer

IGTP researchers identify a potential therapeutic strategy for malignant tumours associated with neurofibromatosis type 1

Copper-induced cell death may help overcome immunotherapy resistance

Blocking a female-only GABA signal that helps glioblastoma evade immunity may boost survival

Pancreatic cancer discovery advances toward first-of-its-kind clinical trial

Foundational research points to new therapeutic strategies for an emerging cancer drug

Sugar-coated nanoparticles show promise for treating most aggressive form of brain cancer

Gramine suppresses triple-negative breast cancer by inducing ferroptosis via CUL3-mediated ubiquitination of MTDH

Eliminating cancer cells that survive KRAS inhibition: A potential way to prevent relapse

CAR T cell therapy leads to 10-year remissions in B-cell lymphoma patients

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