Solving a decades-old structural mystery surrounding the birth of energy-storing lipid droplets

https://phys.org/news/2022-02-decades-old-mystery-birth-energy-storing-lipid.html

"Cryo-EM uses flash-frozen samples, electron beams, and an electron detector rather than a camera to gather data on biological structures at near-atomic scale. Using cryo-EM enabled the researchers to determine that the donut they hypothesized was actually a 10-unit cage... passing enzymes can break down the LDs and free the fatty acids inside to provide energy such as during times of starvation"