Light-controlled 'drug-free' macromolecules for precise tumor therapy

https://phys.org/news/2022-01-light-controlled-drug-free-macromolecules-precise-tumor.html

"The up-conversion nanoparticles converted near-infrared light into ultra-violet light and induced the cross-linking of CA groups, thus resulting in the clustering of CD20 receptors and cell apoptosis. No apoptosis occurred in light-free sites. Therefore, tumors could be precisely treated in a safe and efficient manner. This strategy was confirmed by in situ and intravenous administration in tumor model animals"