Century-old scientific debate settled: anesthesia’s effect on consciousness solved

https://scitechdaily.com/century-old-scientific-debate-settled-anesthesias-effect-on-consciousness-solved/

"Do anesthetics act directly on cell-membrane gates called ion channels, or do they somehow act on the membrane to signal cell changes in a new and unexpected way? It has taken nearly five years of experiments, calls, debates and challenges to arrive at the conclusion that it’s a two-step process that begins in the membrane, the duo say. The anesthetics perturb ordered lipid clusters within the cell membrane known as “lipid rafts” to initiate the signal"