Longevity protein Klotho is a factor in young blood that helps rejuvenate aged mouse muscle

https://medicalxpress.com/news/2021-12-factor-young-blood-rejuvenate-aged.html

"As we age, our muscles gradually become smaller, weaker and less able to heal after injury... circulating shuttles called extracellular vesicles, or EVs, deliver genetic instructions for the longevity protein known as Klotho to muscle cells. Loss of muscle function and impaired muscle repair in old mice may be driven by aged EVs, which carry fewer copies of these instructions than those in young animals... could advance muscle regeneration therapies for older people" See also: "Young blood" particles that help old mice fight aging identified https://newatlas.com/medical/anti-aging-young-blood-particles/

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