Discovery furthers development of novel non-opioid painkillers (analgesics) to safely and effectively treat neuropathic pain


"can provide much more selective targeting of the A1 receptor by binding to a different region of the protein than traditional, previously investigated, activators... minimal unwanted effects... increase their level of effectiveness as the pain signals in the spinal cord get stronger"

Related:

Long-lasting pain relief without opioids: UB researchers develop a novel, local treatment for chronic pain
http://www.buffalo.edu/news/releases/2021/10/001.html "Even under conditions that promote hyperactivity in pain neurons, the researchers found they could significantly reduce this hyperactivity — and therefore pain perception — when they prevented endocytosis with their novel peptide molecule. By inhibiting endocytosis, we are able to prevent pain-sensing neurons from relaying pain information to the central nervous system”

Pain relief without side effects with promising technique

Study could pave way for creating safer opioids

New compound provides innovative pain relief

Can a dangerous microbe offer a new way to silence pain?

On a mission to alleviate chronic pain

Love hormone oxytocin shown to chill out fierce lions

Non-opioid compounds squelch pain without sedation

Possible new way to reduce pain inspired by chickens

Alternative pain control circuits in the brain found to produce relief similar to opioids without the downsides

New compound outperforms pain drug by indirectly targeting calcium channels

Blockbuster experimental drug cuts off pain at the source and isn't addictive - so could it solve the opioid epidemic?
https://www.dailymail.co.uk/health/article-13023793/Blockbuster-experimental-drug-cuts-pain-source-isnt-addictive-solve-opioid-epidemic.html

Comments

Post a Comment